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A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity
Endocytosis is a mechanism by which cells sense their environment and internalize various nutrients, growth factors and signaling molecules. This process initiates at the plasma membrane, converges with autophagy, and terminates at the lysosome. It is well-established that cellular uptake of antisen...
Autores principales: | Ochaba, Joseph, Powers, Andrew F, Tremble, Kaitlyn A, Greenlee, Sarah, Post, Noah M, Matson, John E, MacLeod, A Robert, Guo, Shuling, Aghajan, Mariam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868497/ https://www.ncbi.nlm.nih.gov/pubmed/31612951 http://dx.doi.org/10.1093/nar/gkz901 |
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