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Meiotic Kinetochores Fragment into Multiple Lobes upon Cohesin Loss in Aging Eggs
Chromosome segregation errors during female meiosis are a leading cause of pregnancy loss and human infertility. The segregation of chromosomes is driven by interactions between spindle microtubules and kinetochores. Kinetochores in mammalian oocytes are subjected to special challenges: they need to...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868511/ https://www.ncbi.nlm.nih.gov/pubmed/31679939 http://dx.doi.org/10.1016/j.cub.2019.09.006 |