Butyrophilin-like 3 Directly Binds a Human Vγ4(+) T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen

Butyrophilin (BTN) and butyrophilin-like (BTNL/Btnl) heteromers are major regulators of human and mouse γδ T cell subsets, but considerable contention surrounds whether they represent direct γδ T cell receptor (TCR) ligands. We demonstrate that the BTNL3 IgV domain binds directly and specifically to...

Descripción completa

Detalles Bibliográficos
Autores principales: Willcox, Carrie R., Vantourout, Pierre, Salim, Mahboob, Zlatareva, Iva, Melandri, Daisy, Zanardo, Leonor, George, Roger, Kjaer, Svend, Jeeves, Mark, Mohammed, Fiyaz, Hayday, Adrian C., Willcox, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868513/
https://www.ncbi.nlm.nih.gov/pubmed/31628053
http://dx.doi.org/10.1016/j.immuni.2019.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868513/
https://www.ncbi.nlm.nih.gov/pubmed/31628053
http://dx.doi.org/10.1016/j.immuni.2019.09.006

Ejemplares similares