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Butyrophilin-like 3 Directly Binds a Human Vγ4(+) T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen

Butyrophilin (BTN) and butyrophilin-like (BTNL/Btnl) heteromers are major regulators of human and mouse γδ T cell subsets, but considerable contention surrounds whether they represent direct γδ T cell receptor (TCR) ligands. We demonstrate that the BTNL3 IgV domain binds directly and specifically to...

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Detalles Bibliográficos
Autores principales:	Willcox, Carrie R., Vantourout, Pierre, Salim, Mahboob, Zlatareva, Iva, Melandri, Daisy, Zanardo, Leonor, George, Roger, Kjaer, Svend, Jeeves, Mark, Mohammed, Fiyaz, Hayday, Adrian C., Willcox, Benjamin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868513/ https://www.ncbi.nlm.nih.gov/pubmed/31628053 http://dx.doi.org/10.1016/j.immuni.2019.09.006

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