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N‐Palmitoylglycine and other N‐acylamides activate the lipid receptor G2A/GPR132

The G‐protein‐coupled receptor GPR132, also known as G2A, is activated by 9‐hydroxyoctadecadienoic acid (9‐HODE) and other oxidized fatty acids. Other suggested GPR132 agonists including lysophosphatidylcholine (LPC) have not been readily reproduced. Here, we identify N‐acylamides in particular N‐ac...

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Detalles Bibliográficos
Autores principales: Foster, James R., Ueno, Shohta, Chen, Mao Xiang, Harvey, Jenni, Dowell, Simon J., Irving, Andrew J., Brown, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868653/
https://www.ncbi.nlm.nih.gov/pubmed/31768260
http://dx.doi.org/10.1002/prp2.542