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BTLA blockade enhances Cancer therapy by inhibiting IL-6/IL-10-induced CD19(high) B lymphocytes

BACKGROUND: The standard treatment for epithelial ovarian carcinoma (EOC) is surgery followed by platinum/paclitaxel-based chemotherapy, but the overall survival rate is poor. The purpose of this study was to investigate the therapeutic potential of chemotherapy combined with inhibition of B and T l...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Li, Lin, Han-Wei, Chien, Chung-Liang, Lai, Yen-Ling, Sun, Wei-Zen, Chen, Chi-An, Cheng, Wen-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868712/
https://www.ncbi.nlm.nih.gov/pubmed/31753019
http://dx.doi.org/10.1186/s40425-019-0744-4