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SIMLIN: a bioinformatics tool for prediction of S-sulphenylation in the human proteome based on multi-stage ensemble-learning models

BACKGROUND: S-sulphenylation is a ubiquitous protein post-translational modification (PTM) where an S-hydroxyl (−SOH) bond is formed via the reversible oxidation on the Sulfhydryl group of cysteine (C). Recent experimental studies have revealed that S-sulphenylation plays critical roles in many biol...

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Detalles Bibliográficos
Autores principales: Wang, Xiaochuan, Li, Chen, Li, Fuyi, Sharma, Varun S., Song, Jiangning, Webb, Geoffrey I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868744/
https://www.ncbi.nlm.nih.gov/pubmed/31752668
http://dx.doi.org/10.1186/s12859-019-3178-6