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Synergism of wt-p53 and synthetic material in local nano-TAE gene therapy of hepatoma: comparison of four systems and the possible mechanism

BACKGROUND: TAE-gene therapy for hepatoma, incorporating the tumor-targeted therapeutic efficacy of trans-arterial embolization, hydroxyapatite nanoparticles (nHAP) and anti-cancer wild-type p53 gene (wt-p53), was presented in our former studies (Int J Nanomedicine 8:3757-68, 2013, Liver Int 32:998-...

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Detalles Bibliográficos
Autores principales: Li, Gaopeng, Kang, Wenqin, Jin, Mingliang, Zhang, Lidong, Zheng, Jian, Jia, Kai, Ma, Jinfeng, Liu, Ting, Dang, Xueyi, Yan, Zhifeng, Gao, Zefeng, Xu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868790/
https://www.ncbi.nlm.nih.gov/pubmed/31747895
http://dx.doi.org/10.1186/s12885-019-6162-7