Nickel-Catalyzed Amidoalkylation Reaction of γ-Hydroxy Lactams: An Access to 3-Substituted Isoindolinones†

[Image: see text] An efficient Ni(ClO(4))(2)·6H(2)O-promoted amidoalkylation reaction for the synthesis of 3-substituted isoindolinones involving various γ-hydroxy lactams and nucleophiles has been successfully developed. The transformation proceeds with both carbon (ketones and arenes) and heteroat...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Shi, Xinhua, Li, Jichao, Hou, Zitong, Song, Zihe, Su, Xiaofeng, Peng, Dan, Wang, Feng, Yu, Yitao, Zhao, Guilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868882/
https://www.ncbi.nlm.nih.gov/pubmed/31763566
http://dx.doi.org/10.1021/acsomega.9b02853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868882/
https://www.ncbi.nlm.nih.gov/pubmed/31763566
http://dx.doi.org/10.1021/acsomega.9b02853

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