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Role of Subunit D in Ubiquinone-Binding Site of Vibrio cholerae NQR: Pocket Flexibility and Inhibitor Resistance

[Image: see text] The ion-pumping NADH: ubiquinone dehydrogenase (NQR) is a vital component of the respiratory chain of numerous species of marine and pathogenic bacteria, including Vibrio cholerae. This respiratory enzyme couples the transfer of electrons from NADH to ubiquinone (UQ) to the pumping...

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Detalles Bibliográficos
Autores principales: Raba, Daniel A., Yuan, Ming, Fang, Xuan, Menzer, William M., Xie, Bing, Liang, Pingdong, Tuz, Karina, Minh, David D. L., Juárez, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868883/
https://www.ncbi.nlm.nih.gov/pubmed/31763556
http://dx.doi.org/10.1021/acsomega.9b02707