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Small Polar Hits against S. aureus: Screening, Initial Hit Optimization, and Metabolomic Studies
[Image: see text] The global prevalence of antibacterial resistance requires new antibacterial drugs with novel chemical scaffolds and modes of action. It is also vital to design compounds with optimal physicochemical properties to permeate the bacterial cell envelope. We described an approach of co...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869403/ https://www.ncbi.nlm.nih.gov/pubmed/31763544 http://dx.doi.org/10.1021/acsomega.9b02507 |