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Adipose tissue–derived stromal cells’ conditioned medium modulates endothelial‐mesenchymal transition induced by IL‐1β/TGF‐β2 but does not restore endothelial function

OBJECTIVES: Endothelial cells undergo TGF‐β–driven endothelial‐mesenchymal transition (EndMT), representing up to 25% of cardiac myofibroblasts in ischaemic hearts. Previous research showed that conditioned medium of adipose tissue–derived stromal cells (ASC‐CMed) blocks the activation of fibroblast...

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Detalles Bibliográficos
Autores principales: Liguori, Tácia Tavares Aquinas, Liguori, Gabriel Romero, Moreira, Luiz Felipe Pinho, Harmsen, Martin Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869467/
https://www.ncbi.nlm.nih.gov/pubmed/31468648
http://dx.doi.org/10.1111/cpr.12629