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Adipose tissue–derived stromal cells’ conditioned medium modulates endothelial‐mesenchymal transition induced by IL‐1β/TGF‐β2 but does not restore endothelial function
OBJECTIVES: Endothelial cells undergo TGF‐β–driven endothelial‐mesenchymal transition (EndMT), representing up to 25% of cardiac myofibroblasts in ischaemic hearts. Previous research showed that conditioned medium of adipose tissue–derived stromal cells (ASC‐CMed) blocks the activation of fibroblast...
Autores principales: | Liguori, Tácia Tavares Aquinas, Liguori, Gabriel Romero, Moreira, Luiz Felipe Pinho, Harmsen, Martin Conrad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869467/ https://www.ncbi.nlm.nih.gov/pubmed/31468648 http://dx.doi.org/10.1111/cpr.12629 |
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