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GIT1 regulates angiogenic factor secretion in bone marrow mesenchymal stem cells via NF‐κB/Notch signalling to promote angiogenesis

OBJECTIVES: Osteogenesis is coupled with angiogenesis during bone remodelling. G‐protein‐coupled receptor (GPCR) kinase 2‐interacting protein‐1 (GIT1) is an important protein that participates in fracture healing by regulating angiogenesis. This study investigated whether GIT1 could affect bone mese...

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Detalles Bibliográficos
Autores principales: Li, Linwei, Tang, Pengyu, Zhou, Zheng, Wang, Qian, Xu, Tao, Zhao, Shujie, Huang, Yifan, Kong, Fanqi, Liu, Wei, Cheng, Lin, Zhou, Zhimin, Zhao, Xuan, Gu, Changjiang, Luo, Yongjun, Tao, Gaojian, Qian, Dingfei, Chen, Jian, Fan, Jin, Yin, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6869488/
https://www.ncbi.nlm.nih.gov/pubmed/31502302
http://dx.doi.org/10.1111/cpr.12689