DNA Methylation Cancer Biomarkers: Translation to the Clinic

Carcinogenesis is accompanied by widespread DNA methylation changes within the cell. These changes are characterized by a globally hypomethylated genome with focal hypermethylation of numerous 5’-cytosine-phosphate-guanine-3’ (CpG) islands, often spanning gene promoters and first exons. Many of thes...

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Detalles Bibliográficos
Autores principales: Locke, Warwick J., Guanzon, Dominic, Ma, Chenkai, Liew, Yi Jin, Duesing, Konsta R., Fung, Kim Y.C., Ross, Jason P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6870840/
https://www.ncbi.nlm.nih.gov/pubmed/31803237
http://dx.doi.org/10.3389/fgene.2019.01150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6870840/
https://www.ncbi.nlm.nih.gov/pubmed/31803237
http://dx.doi.org/10.3389/fgene.2019.01150

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