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Biological characterization of expression quantitative trait loci (eQTLs) showing tissue-specific opposite directional effects

Interpreting the susceptible loci documented by genome-wide association studies (GWASs) is of utmost importance in the post-GWAS era. Since most complex traits are contributed by multiple tissues, analyzing tissue-specific effects of expression quantitative trait loci (eQTLs) is a promising approach...

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Detalles Bibliográficos
Autores principales: Mizuno, Akira, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871526/
https://www.ncbi.nlm.nih.gov/pubmed/31296926
http://dx.doi.org/10.1038/s41431-019-0468-4