Prospective head-to-head comparison of accuracy of two sequencing platforms for screening for fetal aneuploidy by cell-free DNA: the PEGASUS study

We compared clinical validity of two non-invasive prenatal screening (NIPS) methods for fetal trisomies 13, 18, 21, and monosomy X. We recruited prospectively 2203 women at high risk of fetal aneuploidy and 1807 at baseline risk. Three-hundred and twenty-nine euploid samples were randomly removed. T...

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Detalles Bibliográficos
Autores principales: Rousseau, François, Langlois, Sylvie, Johnson, Jo-Ann, Gekas, Jean, Bujold, Emmanuel, Audibert, François, Walker, Mark, Giroux, Sylvie, Caron, André, Clément, Valérie, Blais, Jonatan, MacLeod, Tina, Moore, Richard, Gauthier, Julie, Jouan, Loubna, Laporte, Alexandre, Diallo, Ousmane, Parker, Jeremy, Swanson, Lucas, Zhao, Yongjun, Labelle, Yves, Giguère, Yves, Forest, Jean-Claude, Little, Julian, Karsan, Aly, Rouleau, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871532/
https://www.ncbi.nlm.nih.gov/pubmed/31231136
http://dx.doi.org/10.1038/s41431-019-0443-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871532/
https://www.ncbi.nlm.nih.gov/pubmed/31231136
http://dx.doi.org/10.1038/s41431-019-0443-0

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