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APOE-knockout in rabbits causes loss of cells in nucleus pulposus and enhances the levels of inflammatory catabolic cytokines damaging the intervertebral disc matrix

Rabbits with naturally high levels of cholesterol ester transfer protein (CETP), unlike rodents, have become an interesting animal model for the study of lipid metabolism and atherosclerosis, as they have similarities to humans in lipid metabolism, cardiovascular physiology and susceptibility to dev...

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Detalles Bibliográficos
Autores principales: Beierfuß, Anja, Hunjadi, Monika, Ritsch, Andreas, Kremser, Christian, Thomé, Claudius, Mern, Demissew Shenegelegn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6871866/
https://www.ncbi.nlm.nih.gov/pubmed/31751427
http://dx.doi.org/10.1371/journal.pone.0225527