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Uncovering the subtype-specific temporal order of cancer pathway dysregulation

Cancer is driven by genetic mutations that dysregulate pathways important for proper cell function. Therefore, discovering these cancer pathways and their dysregulation order is key to understanding and treating cancer. However, the heterogeneity of mutations between different individuals makes this...

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Detalles Bibliográficos
Autores principales: Khakabimamaghani, Sahand, Ding, Dujian, Snow, Oliver, Ester, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872169/
https://www.ncbi.nlm.nih.gov/pubmed/31710622
http://dx.doi.org/10.1371/journal.pcbi.1007451