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Uncovering the subtype-specific temporal order of cancer pathway dysregulation
Cancer is driven by genetic mutations that dysregulate pathways important for proper cell function. Therefore, discovering these cancer pathways and their dysregulation order is key to understanding and treating cancer. However, the heterogeneity of mutations between different individuals makes this...
Autores principales: | Khakabimamaghani, Sahand, Ding, Dujian, Snow, Oliver, Ester, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872169/ https://www.ncbi.nlm.nih.gov/pubmed/31710622 http://dx.doi.org/10.1371/journal.pcbi.1007451 |
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