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Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division

The ability of Mycobacterium tuberculosis (Mtb) to persist in its host is central to the pathogenesis of tuberculosis, yet the underlying mechanisms remain incompletely defined. PerM, an integral membrane protein, is required for persistence of Mtb in mice. Here, we show that perM deletion caused a...

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Detalles Bibliográficos
Autores principales: Wang, Ruojun, Kreutzfeldt, Kaj, Botella, Helene, Vaubourgeix, Julien, Schnappinger, Dirk, Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872210/
https://www.ncbi.nlm.nih.gov/pubmed/31751212
http://dx.doi.org/10.7554/eLife.49570