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Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer

Within triple negative breast cancer, several molecular subtypes have been identified, underlying the heterogeneity of such an aggressive disease. The basal-like subtype is characterized by mutations in the TP53 gene, and is associated with a low pathologic complete response rate following neoadjuva...

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Detalles Bibliográficos
Autores principales: Giordano, Antonio, Liu, Yueying, Armeson, Kent, Park, Yeonhee, Ridinger, Maya, Erlander, Mark, Reuben, James, Britten, Carolyn, Kappler, Christiana, Yeh, Elizabeth, Ethier, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872222/
https://www.ncbi.nlm.nih.gov/pubmed/31751384
http://dx.doi.org/10.1371/journal.pone.0224420