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Polo-like kinase 1 (Plk1) inhibition synergizes with taxanes in triple negative breast cancer
Within triple negative breast cancer, several molecular subtypes have been identified, underlying the heterogeneity of such an aggressive disease. The basal-like subtype is characterized by mutations in the TP53 gene, and is associated with a low pathologic complete response rate following neoadjuva...
Autores principales: | Giordano, Antonio, Liu, Yueying, Armeson, Kent, Park, Yeonhee, Ridinger, Maya, Erlander, Mark, Reuben, James, Britten, Carolyn, Kappler, Christiana, Yeh, Elizabeth, Ethier, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872222/ https://www.ncbi.nlm.nih.gov/pubmed/31751384 http://dx.doi.org/10.1371/journal.pone.0224420 |
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