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Ribosome Evolution and Structural Capacitance

In addition to the canonical loss-of-function mutations, mutations in proteins may additionally result in gain-of-function through the binary activation of cryptic “structural capacitance elements.” Our previous bioinformatic analysis allowed us to propose a new mechanism of protein evolution – stru...

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Detalles Bibliográficos
Autores principales: Buckle, Ashley M., Buckle, Malcolm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872460/
https://www.ncbi.nlm.nih.gov/pubmed/31803754
http://dx.doi.org/10.3389/fmolb.2019.00123