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Ribosome Evolution and Structural Capacitance
In addition to the canonical loss-of-function mutations, mutations in proteins may additionally result in gain-of-function through the binary activation of cryptic “structural capacitance elements.” Our previous bioinformatic analysis allowed us to propose a new mechanism of protein evolution – stru...
Autores principales: | Buckle, Ashley M., Buckle, Malcolm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872460/ https://www.ncbi.nlm.nih.gov/pubmed/31803754 http://dx.doi.org/10.3389/fmolb.2019.00123 |
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