Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response

Chlorthalidone (CTD) is more potent than hydrochlorothiazide (HCTZ) in reducing blood pressure (BP) in hypertensive patients, though both are plagued with BP response variability. However, there is a void in the literature regarding the genetic determinants contributing to the variability observed i...

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Detalles Bibliográficos
Autores principales: Singh, Sonal, McDonough, Caitrin W., Gong, Yan, Bailey, Kent R., Boerwinkle, Eric, Chapman, Arlene B., Gums, John G., Turner, Stephen T., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872535/
https://www.ncbi.nlm.nih.gov/pubmed/31754133
http://dx.doi.org/10.1038/s41598-019-53345-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872535/
https://www.ncbi.nlm.nih.gov/pubmed/31754133
http://dx.doi.org/10.1038/s41598-019-53345-5

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