Cargando…

RUNX1 contributes to the mesenchymal subtype of glioblastoma in a TGFβ pathway-dependent manner

Runt-Related Transcription Factor 1 (RUNX1) is highly expressed in the Mesenchymal (Mes) subtype of glioblastoma (GBM). However, the specific molecular mechanism of RUNX1 in Mes GBM remains largely elusive. In this study, cell and tumor tissue typing were performed by RNA-sequencing. Co-immunoprecip...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Kai, Cui, Xiaoteng, Wang, Qixue, Fang, Chuan, Tan, Yanli, Wang, Yunfei, Yi, Kaikai, Yang, Chao, You, Hua, Shang, Rui, Wang, Jiachong, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872557/
https://www.ncbi.nlm.nih.gov/pubmed/31754093
http://dx.doi.org/10.1038/s41419-019-2108-x