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Specific metallo-protein interactions and antimicrobial activity in Histatin-5, an intrinsically disordered salivary peptide
Histatin-5 (Hst-5) is an antimicrobial, salivary protein that is involved in the host defense system. Hst-5 has been proposed to bind functionally relevant zinc and copper but presents challenges in structural studies due to its disordered conformation in aqueous solution. Here, we used circular dic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872563/ https://www.ncbi.nlm.nih.gov/pubmed/31754129 http://dx.doi.org/10.1038/s41598-019-52676-7 |