Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells

PD-1 is a target of cancer immunotherapy but responses are limited to a fraction of patients. Identifying patients with T cells subjected to PD-1-mediated inhibition will allow selection of suitable candidates for PD-1-blocking therapy and will improve the therapeutic success. We sought to develop a...

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Detalles Bibliográficos
Autores principales: Bardhan, Kankana, Aksoylar, Halil-Ibrahim, Le Bourgeois, Thibault, Strauss, Laura, Weaver, Jessica D., Delcuze, Bethany, Charest, Alain, Patsoukis, Nikolaos, Boussiotis, Vassiliki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872651/
https://www.ncbi.nlm.nih.gov/pubmed/31754127
http://dx.doi.org/10.1038/s41598-019-53463-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872651/
https://www.ncbi.nlm.nih.gov/pubmed/31754127
http://dx.doi.org/10.1038/s41598-019-53463-0

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