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EC313-a tissue selective SPRM reduces the growth and proliferation of uterine fibroids in a human uterine fibroid tissue xenograft model

Uterine fibroids (UFs) are associated with irregular or excessive uterine bleeding, pelvic pain or pressure, or infertility. Ovarian steroid hormones support the growth and maintenance of UFs. Ulipristal acetate (UPA) a selective progesterone receptor (PR) modulator (SPRM) reduce the size of UFs, in...

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Detalles Bibliográficos
Autores principales: Nair, Hareesh B., Santhamma, Bindu, Dileep, Kalarickal V., Binkley, Peter, Acosta, Kirk, Zhang, Kam Y. J., Schenken, Robert, Nickisch, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872653/
https://www.ncbi.nlm.nih.gov/pubmed/31754172
http://dx.doi.org/10.1038/s41598-019-53467-w