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Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human

Recent progress has enabled the conversion of primed human embryonic stem cells (hESCs) to the naive state of pluripotency, resembling the well-characterized naive mouse ESCs (mESCs). However, a thorough histone epigenetic characterization of this conversion process is currently lacking, while its l...

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Detalles Bibliográficos
Autores principales: De Clerck, Laura, Taelman, Jasin, Popovic, Mina, Willems, Sander, Van der Jeught, Margot, Heindryckx, Björn, De Sutter, Petra, Marks, Hendrik, Deforce, Dieter, Dhaenens, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872658/
https://www.ncbi.nlm.nih.gov/pubmed/31754138
http://dx.doi.org/10.1038/s41598-019-53681-6