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Untargeted histone profiling during naive conversion uncovers conserved modification markers between mouse and human
Recent progress has enabled the conversion of primed human embryonic stem cells (hESCs) to the naive state of pluripotency, resembling the well-characterized naive mouse ESCs (mESCs). However, a thorough histone epigenetic characterization of this conversion process is currently lacking, while its l...
Autores principales: | De Clerck, Laura, Taelman, Jasin, Popovic, Mina, Willems, Sander, Van der Jeught, Margot, Heindryckx, Björn, De Sutter, Petra, Marks, Hendrik, Deforce, Dieter, Dhaenens, Maarten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872658/ https://www.ncbi.nlm.nih.gov/pubmed/31754138 http://dx.doi.org/10.1038/s41598-019-53681-6 |
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