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A novel 40kDa N-terminal truncated carboxypeptidase E splice variant: cloning, cDNA sequence analysis and role in regulation of metastatic genes in human cancers

Carboxypeptidase E (CPE), a prohormone processing enzyme, is a 476- amino acid protein with a signal peptide in its N-terminus and is expressed in the nervous and the endocrine systems. Recent evidence indicate CPE plays various non-enzymatic roles in the endocrine and nervous systems and in various...

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Detalles Bibliográficos
Autores principales: Yang, Xuyu, Lou, Hong, Chen, Ya-Ting, Huang, Shui-Feng, Loh, Y. Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872665/
https://www.ncbi.nlm.nih.gov/pubmed/31798768
http://dx.doi.org/10.18632/genesandcancer.193