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Secreting-lux/pT-ClyA engineered bacteria suppresses tumor growth via interleukin-1β in two pathways

Engineered Salmonella typhimurium (S.t-ΔpG(lux/pT-ClyA)) and attenuated Salmonella typhimurium (SL: Salmonella typhimurium with a defect in the synthesis of guanine 5′-diphosphate-3′-diphosphate) exhibit similar tumor targeting capabilities (Kim et al. in Theranostics 5:1328–1342, 2015; Jiang et al....

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Detalles Bibliográficos
Autores principales: Wu, Yuqin, Feng, Zhicai, Jiang, Shengnan, Chen, Jing, Zhan, Yuefu, Chen, Jianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872689/
https://www.ncbi.nlm.nih.gov/pubmed/31754923
http://dx.doi.org/10.1186/s13568-019-0910-6