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Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

Patients with bipolar disorder (BD) show higher frequency of obesity and type 2 diabetes (T2D), but the underlying genetic determinants and molecular pathways are not well studied. Using large publicly available datasets, we (1) conducted a gene-based analysis using MAGMA to identify genes associate...

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Detalles Bibliográficos
Autores principales: Pisanu, Claudia, Williams, Michael J., Ciuculete, Diana M., Olivo, Gaia, Del Zompo, Maria, Squassina, Alessio, Schiöth, Helgi B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872724/
https://www.ncbi.nlm.nih.gov/pubmed/31754094
http://dx.doi.org/10.1038/s41398-019-0652-x