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Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure

During viral infections viruses express molecules that interfere with the host-cell death machinery and thus inhibit cell death responses. For example the viral FLIP (vFLIP) encoded by Kaposi’s sarcoma-associated herpesvirus interacts and inhibits the central cell death effector, Caspase-8. In order...

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Detalles Bibliográficos
Autores principales: Bittel, Miriam, Kremer, Andreas E., Stürzl, Michael, Wirtz, Stefan, Stolzer, Iris, Neurath, Markus F., Ballon, Gianna, Günther, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872756/
https://www.ncbi.nlm.nih.gov/pubmed/31754092
http://dx.doi.org/10.1038/s41419-019-2115-y