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Serine substitutions are linked to codon usage and differ for variable and conserved protein regions

Serine is the only amino acid that is encoded by two disjoint codon sets (TCN & AGY) so that a tandem substitution of two nucleotides is required to switch between the two sets. We show that these codon sets underlie distinct substitution patterns at positions subject to purifying and diversifyi...

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Detalles Bibliográficos
Autores principales: Schwartz, Gregory W., Shauli, Tair, Linial, Michal, Hershberg, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872785/
https://www.ncbi.nlm.nih.gov/pubmed/31754132
http://dx.doi.org/10.1038/s41598-019-53452-3