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Serine substitutions are linked to codon usage and differ for variable and conserved protein regions
Serine is the only amino acid that is encoded by two disjoint codon sets (TCN & AGY) so that a tandem substitution of two nucleotides is required to switch between the two sets. We show that these codon sets underlie distinct substitution patterns at positions subject to purifying and diversifyi...
Autores principales: | Schwartz, Gregory W., Shauli, Tair, Linial, Michal, Hershberg, Uri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872785/ https://www.ncbi.nlm.nih.gov/pubmed/31754132 http://dx.doi.org/10.1038/s41598-019-53452-3 |
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