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APC loss affects DNA damage repair causing doxorubicin resistance in breast cancer cells

Chemoresistance is one of the leading causes of cancer-related deaths in the United States. Triple negative breast cancer (TNBC), a subtype lacking the known breast cancer receptors used for targeted therapy, is reliant on chemotherapy as the standard of care. The Adenomatous Polyposis Coli (APC) tu...

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Detalles Bibliográficos
Autores principales: Stefanski, Casey D., Keffler, Kaitlyn, McClintock, Stephanie, Milac, Lauren, Prosperi, Jenifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872841/
https://www.ncbi.nlm.nih.gov/pubmed/31759252
http://dx.doi.org/10.1016/j.neo.2019.09.002