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Discovery of novel helix binding sites at protein-protein interfaces
Protein-protein interactions (PPIs) play a key role in numerous biological processes. Many efforts have been undertaken to develop PPI modulators for therapeutic applications; however, to date, most of the peptide binders designed to target PPIs are derived from native binding helices or using the n...
Autores principales: | Yang, Wei, Sun, Xiangyu, Zhang, Changsheng, Lai, Luhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872852/ https://www.ncbi.nlm.nih.gov/pubmed/31768230 http://dx.doi.org/10.1016/j.csbj.2019.11.001 |
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