Anhydroecgonine methyl ester (AEME), a cocaine pyrolysis product, impairs glutathione-related enzymes response and increases lipid peroxidation in the hippocampal cell culture

Crack cocaine smokers inhale, alongside with cocaine, its pyrolysis product, anhydroecgonine methyl ester (AEME). We have previously described AEME neurotoxic effect and its additive effect when co-incubated with cocaine. Our aim was to evaluate, the effect of AEME, cocaine and AEME-cocaine combinat...

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Detalles Bibliográficos
Autores principales: Garcia, Raphael Caio Tamborelli, Torres, Larissa Lobo, Dati, Livia Mendonça Munhoz, Loureiro, Ana Paula de Melo, Afeche, Solange Castro, Sandoval, Maria Regina Lopes, Marcourakis, Tania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872858/
https://www.ncbi.nlm.nih.gov/pubmed/31768333
http://dx.doi.org/10.1016/j.toxrep.2019.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872858/
https://www.ncbi.nlm.nih.gov/pubmed/31768333
http://dx.doi.org/10.1016/j.toxrep.2019.11.001

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