Furin-Mediated Intracellular Self-Assembly of Olsalazine Nanoparticles for Enhanced Magnetic Resonance Imaging and Tumor Therapy

One strategy to enhance tumor retention of imaging agents or anti-cancer drugs is rational design of probes that undergo a tumor-specific enzymatic reaction which prevents them from being pumped out of the cell. Here, the anticancer agent olsalazine (Olsa) was conjugated to the cell-penetrating pept...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Yue, Zhang, Jia, Qi, Xiaoliang, Li, Shuoguo, Liu, Guanshu, Siddhanta, Soumik, Barman, Ishan, Song, Xiaolei, McMahon, Michael T., Bulte, Jeff W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872935/
https://www.ncbi.nlm.nih.gov/pubmed/31636420
http://dx.doi.org/10.1038/s41563-019-0503-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872935/
https://www.ncbi.nlm.nih.gov/pubmed/31636420
http://dx.doi.org/10.1038/s41563-019-0503-4

Ejemplares similares