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MIM-Deficient Mice Exhibit Anatomical Changes in Dendritic Spines, Cortex Volume and Brain Ventricles, and Functional Changes in Motor Coordination and Learning

In this study, we performed a comprehensive behavioral and anatomical analysis of the Missing in Metastasis (Mtss1/MIM) knockout (KO) mouse brain. We also analyzed the expression of MIM in different brain regions at different ages. MIM is an I-BAR containing membrane curving protein, shown to be inv...

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Detalles Bibliográficos
Autores principales: Minkeviciene, Rimante, Hlushchenko, Iryna, Virenque, Anaïs, Lahti, Lauri, Khanal, Pushpa, Rauramaa, Tuomas, Koistinen, Arto, Leinonen, Ville, Noe, Francesco M., Hotulainen, Pirta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872969/
https://www.ncbi.nlm.nih.gov/pubmed/31803019
http://dx.doi.org/10.3389/fnmol.2019.00276