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Modulation of Calretinin Expression in Human Mesothelioma Cells Reveals the Implication of the FAK and Wnt Signaling Pathways in Conferring Chemoresistance towards Cisplatin

Malignant mesothelioma (MM) is an aggressive asbestos-linked neoplasm, characterized by dysregulation of signaling pathways. Due to intrinsic or acquired chemoresistance, MM treatment options remain limited. Calretinin is a Ca(2+)-binding protein expressed during MM tumorigenesis that activates the...

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Detalles Bibliográficos
Autores principales: Wörthmüller, Janine, Salicio, Valérie, Oberson, Anne, Blum, Walter, Schwaller, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873109/
https://www.ncbi.nlm.nih.gov/pubmed/31671889
http://dx.doi.org/10.3390/ijms20215391