Off-Target Effects in Transgenic Mice: Characterization of Dopamine Transporter (DAT)-Cre Transgenic Mouse Lines Exposes Multiple Non-Dopaminergic Neuronal Clusters Available for Selective Targeting within Limbic Neurocircuitry

Transgenic mouse lines are instrumental in our attempt to understand brain function. Promoters driving transgenic expression of the gene encoding Cre recombinase are crucial to ensure selectivity in Cre-mediated targeting of floxed alleles using the Cre-Lox system. For the study of dopamine (DA) neu...

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Detalles Bibliográficos
Autores principales: Papathanou, Maria, Dumas, Sylvie, Pettersson, Hanna, Olson, Lars, Wallén-Mackenzie, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873162/
https://www.ncbi.nlm.nih.gov/pubmed/31481399
http://dx.doi.org/10.1523/ENEURO.0198-19.2019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873162/
https://www.ncbi.nlm.nih.gov/pubmed/31481399
http://dx.doi.org/10.1523/ENEURO.0198-19.2019

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