Sarcosine promotes trafficking of dendritic cells and improves efficacy of anti-tumor dendritic cell vaccines via CXC chemokine family signaling

BACKGROUND: Dendritic cell (DC) vaccine efficacy is directly related to the efficiency of DC migration to the lymph node after delivery to the patient. We discovered that a naturally occurring metabolite, sarcosine, increases DC migration in human and murine cells resulting in significantly improved...

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Detalles Bibliográficos
Autores principales: Dastmalchi, Farhad, Karachi, Aida, Yang, Changlin, Azari, Hassan, Sayour, Elias Joseph, Dechkovskaia, Anjelika, Vlasak, Alexander Loren, Saia, Megan Ellen, Lovaton, Rolando Eladio, Mitchell, Duane Anthony, Rahman, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873439/
https://www.ncbi.nlm.nih.gov/pubmed/31753028
http://dx.doi.org/10.1186/s40425-019-0809-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873439/
https://www.ncbi.nlm.nih.gov/pubmed/31753028
http://dx.doi.org/10.1186/s40425-019-0809-4

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