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Four novel mutations in the mitochondrial ND4 gene of complex I in patients with multiple sclerosis

Multiple sclerosis (MS) is an immune-mediated neurological, inflammatory disease of the central nervous system. Recent studies have suggested that genetic variants in mitochondrial DNA (mtDNA)-encoded complexes of respiratory chain, particularly, complex I (NADH dehydrogenase), contribute to the pat...

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Detalles Bibliográficos
Autores principales: Alharbi, Maram Atallah, Al-Kafaji, Ghada, Khalaf, Noureddine Ben, Messaoudi, Safia Abdulsalam, Taha, Safa, Daif, Abdulqader, Bakhiet, Moiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873451/
https://www.ncbi.nlm.nih.gov/pubmed/31798871
http://dx.doi.org/10.3892/br.2019.1250