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The osteogenic differentiation of human adipose-derived stem cells is regulated through the let-7i-3p/LEF1/β-catenin axis under cyclic strain

BACKGROUND: The Wnt/β-catenin pathway is involved in the osteogenic differentiation of human adipose-derived stem cells (hASCs) under cyclic strain. Very little is known about the role of microRNAs in these events. METHODS: Cells were obtained using enzyme digestion methods, and proliferation was de...

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Detalles Bibliográficos
Autores principales: Luo, Yadong, Ge, Ran, Wu, Heming, Ding, Xu, Song, Haiyang, Ji, Huan, Li, Meng, Ma, Yunan, Li, Sheng, Wang, Chenxing, Du, Hongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873506/
https://www.ncbi.nlm.nih.gov/pubmed/31753039
http://dx.doi.org/10.1186/s13287-019-1470-z