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Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer

BACKGROUND: Nuclear factor erythroid 2–related factor 2 (Nrf2) is involved in cell proliferation by promotion of metabolic activity. It is also the major regulator of antioxidants and has a pivotal role in tumor cell proliferation and resistance to chemotherapy. Accordingly, we investigated the role...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yoshiyuki, Kamai, Takao, Higashi, Satoru, Murakami, Satoshi, Arai, Kyoko, Shirataki, Hiromichi, Yoshida, Ken-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873559/
https://www.ncbi.nlm.nih.gov/pubmed/31752777
http://dx.doi.org/10.1186/s12885-019-6347-0