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Nrf2 gene mutation and single nucleotide polymorphism rs6721961 of the Nrf2 promoter region in renal cell cancer
BACKGROUND: Nuclear factor erythroid 2–related factor 2 (Nrf2) is involved in cell proliferation by promotion of metabolic activity. It is also the major regulator of antioxidants and has a pivotal role in tumor cell proliferation and resistance to chemotherapy. Accordingly, we investigated the role...
Autores principales: | Yamaguchi, Yoshiyuki, Kamai, Takao, Higashi, Satoru, Murakami, Satoshi, Arai, Kyoko, Shirataki, Hiromichi, Yoshida, Ken-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6873559/ https://www.ncbi.nlm.nih.gov/pubmed/31752777 http://dx.doi.org/10.1186/s12885-019-6347-0 |
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